Pasteur's Quadrant: Basic Science and Technological Innovation Donald E. Stokes
Publisher: Brookings Institution Press

Pasteurs Quadrant: Basic Science and Technological Innovation. Brookings Institution Press 1997 c. Donald Stokes (Pascal's Quadrant: Basic Science and Technological Innovation, 1997) stresses work that is motivated by both considerations for use and fundamental understanding. ÀInstructional Technology: past, present and future》；. ÀPasteur's Quadrant: Basic Science and Technological Innovation》；. (1997) Pasteur's Quadrant: Basic Science and Technological Innovation. But I'm not sure there's enough universally agreed common ground about innovation to talk about a “canon”. His favorite example of “use-inspired basic research” is Louis Pasteur's repeated success in working on genuine problems such as the spoilage of milk and failures of wine fermentation, to produce basic science breakthroughs about bacterial processes and vaccines. One way of making this distinction is in the terms introduced in the infrequently read but oft cited 1997 book by Stokes, called Pasteur's Quadrant – Basic Science and Technological Innovation. A National Biotechnology Strategy for South Africa (2002): http://www.pub.ac.za/pdfs/biotechstrategy_2002.pdf; Stokes, D.E. ÀWorld Wide Research: Reshaping the Science and Humanities》；. He suggested that research in this “Pasteur's quadrant” – use-inspired basic research – should be a priority for public support. Stokes DE: Pasteur's Quadrant: Basic Science and Technological Innovation. Pasteur's Quadrant: Basic Science and Technological Innovation book download Download Pasteur's Quadrant: Basic Science and Technological Innovation Cambridge, MA: The MIT Press. (1997) Pasteur's Quadrant -- Basic Science and Technological Innovation, The Brookings Institute, Washington DC Harvey, M. Washington DC: Brookings Institution Press; 1997. (2012) “Performance-based university research funding systems”, Research Policy, 41(2), 251-261. Collectively, these core technologies could permit the development of an innovative pharmaceutical platform composed of nanoparticles with tethered small interfering RNA (siRNA) oligonucelotides whose sequence and objective can be reprogrammed “on-the-fly” to inhibit multiple targets within multiple classes of And the first element in DARPA's success is the power that lies at the intersection of basic science and application, in the so-called Pasteur's Quadrant. Largely as a result of thinking about nanotechnology (as I discussed a few years ago here and here), I'm less confident any more that there's such a clean break between science and technology, or, for that matter, pure and .